Fig. 5

Putative fungal-specific transcription factor encoding gene cacA is embedded in a F. fomentarius cell wall co-expression network and is conserved in biomaterial-forming fungi. (A) Schematic diagram depicting co-expression pairs (Spearman > 0.4, FDR < 0.05) represented in light grey, with edges connecting to cacA highlighted in black. Only chitin synthase encoding genes 682709 and 1397629 are not co-expressed with cacA. Note remarkable frequency of interconnections to all genes in the network. (B) Putative cacA orthologues from NCBI protein BLASTS in selected fungi. (C) Simple phylogenetic reconstruction of cacA and predicted orthologues generated using [52]